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SIRT2 Inhibitor, AGK2
Cat No.
CEI-0651
Description
A potent inhibitor of sirtuin 2 (SIRT2) (IC50 = 3.5 µM). AGK2 is>15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued α ;-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson’s disease.
Appearance
Yellow solid
Product Overview
A SIRT2 inhibitor
CAS No.
304896-28-4
Molecular Weight
367.44
Purity
>98% by HPLC
Storage
-20 centigrade
Targets
SIRT2
Molecular Formula
C₂₃H₁₃Cl₂N₃O₂
Chemical Name
AGK2, (2E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide
Solubility
DMSO
Shipping Conditions
Gel pack
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