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Senicapoc
Cat No.
CEI-1526
Product Overview
Senicapoc is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ±2 nM (CLT IC50 = 100 ±12 nM) and inhibited RBC dehydration with an IC50 of 30 ±20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia
CAS No.
289656-45-7
Molecular Weight
323.35
Purity
0.98
Storage
Store at -20°C
Synonyms
ICA-17043; ICA 17043; ICA17043
Targets
Gardos channel; RBC
Molecular Formula
C20H15F2NO
Chemical Name
2,2-bis(4-fluorophenyl)-2-phenylacetamide
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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