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SD169

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Cat No.

CEI-1108

Description

SD-169 is an orally available, ATP-competitve, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).

Abbr

SD169(MAPK14)

Alias

RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha

Product Overview

ATP-competitve, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor

CAS No.

1670-87-7

Molecular Weight

160.17

Purity

> 95%

Stability

2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO

Storage

4 centigrade

Synonyms

RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha

Targets

p38α MAP kinase

Molecular Formula

C9H8N2O

Chemical Name

1H-indole-5-carboxamide

Solubility

DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL