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SCD1 Inhibitor
Cat No.
CEI-0644
Description
Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent desaturation index lowering effect. SCD1 inhibition resulted in alterations in macrophage membrane lipid composition and marked hypersensitivity to toll-like receptor 4 agonists.
Alias
A939572
Appearance
Lyophilized solid
Product Overview
A SCD1(stearoyl-CoA desaturase 1) inhibitor
Molecular Weight
695.7
Purity
Single spot by TLC
Storage
-20 centigrade
Synonyms
A939572
Targets
SCD
Molecular Formula
C₂₀H₂₂ClN₃O₃
Chemical Name
4-(2-Chlorophenoxy)-N-(3-(3-methylcarbamoyl)phenyl)piperidine-1-carboxamide
Solubility
DMSO (20 mM)
Shipping Conditions
Gel pack
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