Description
SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 µM) and HDAC3 (IC50 = 0.30 µM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.
Alias
Suberohydroxamic acid; suberic bis-hydroxamic acid; N, N-dihydroxyoctanediamide
Appearance
Light brown solid
Product Overview
A potent HDAC inhibitor
Synonyms
Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N-dihydroxyoctanediamide
Molecular Formula
C 8 H 16 N 2 O 4
Solubility
DMSO (~100 mM) or EtOH (~ 20 mM) or 1 eq. HCl (50 mM)
Shipping Conditions
Gel pack
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