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SB 431542

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Cat No.

CEI-0308

Description

SB 431542 can inhibit SMAD3 with IC50 of 94 nM.

CAS No.

301836-41-9

Molecular Weight

384.39

Purity

>99%

Storage

2 years at -20centigrade Powder

Targets

SMAD3

Molecular Formula

C22H16N4O3

Chemical Name

4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide

Solubility

DMSO 77 mg/mL Water

In vitro

SB-431542 blocks the phosphorylation of SMAD2 in response to TGF-beta.