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SB 431542
Cat No.
CEI-0308
Description
SB 431542 can inhibit SMAD3 with IC50 of 94 nM.
CAS No.
301836-41-9
Molecular Weight
384.39
Purity
>99%
Storage
2 years at -20centigrade Powder
Targets
SMAD3
Molecular Formula
C22H16N4O3
Chemical Name
4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
Solubility
DMSO 77 mg/mL Water
In vitro
SB-431542 blocks the phosphorylation of SMAD2 in response to TGF-beta.
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