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SB 415286

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Cat No.

CEI-0095

Description

SB 415286

CAS No.

264218-23-7

Molecular Weight

359.72

Purity

>99%

Storage

2 years at -20 centigrade

Targets

GSK3-alpha

Molecular Formula

C16H10ClN3O5

Solubility

In vitro

SB 415286 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI3-kinase pathway activity in a concentration-dependent manner, which is correlated with inhibition of GSK-3 activity and modulation of GSK-3 substrates tau and beta-catenin.