Description
It is a highly selective inhibitor of S6K1, with IC50=52nM. It shows moderate risk against 2C9.
Alias
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
Molecular Formula
C17H18N4O3S
Chemical Name
2-(3-(1H-indazol-5-yl)ureido)-5-tert-butylthiophene-3-carboxylic acid
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL