Product Overview
INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor. (IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively). INCB018424 is useful for rheumatoid arthritis.
Synonyms
INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate; Ruxolitinib
Molecular Formula
C17H21N6O4P
Chemical Name
(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile; phosphoric acid
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request