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Roscovitine
Cat No.
CEI-0973
Description
Potent and selective inhibitor of cyclin-dependent kinases displaying higher potency and selectivity compared to olomoucine. p34 cdc2 IC50 = 0.2 uM. Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic. Cell permeable.
Abbr
Roscovitine(GTF2H3, CDK1)
Alias
(R)-2-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl) amino) butan-1-ol
Appearance
White solid
Product Overview
p34/cdc2 inhibitor
CAS No.
179248-59-0
Molecular Weight
354.5
Purity
>99% (TLC); NMR (Conforms)
Synonyms
(R)-2-((6-(benzylamino)-9-isopropyl-9H-purin-2-yl) amino) butan-1-ol
Targets
p34/cdc2
Molecular Formula
C19H26N6O
Solubility
May be dissolved in Ethanol (10mg/ml) or DMSO (10mg/ml, warm)
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