Description
This is an endoribonuclease that cleaves double-stranded RNA molecules. The cleavage can be either a single-stranded nick or double-stranded break in the RNA, depending in part upon the degree of base-pairing in the region of the cleavage site. Specificity is conferred by negative determinants, i.e., the presence of certain Watson-Crick base-pairs at specific positions that strongly inhibit cleavage. RNase III is involved in both rRNA processing and mRNA processing and decay.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
RNase III; ribonuclease 3
Reaction
Endonucleolytic cleavage to a 5'-phosphomonoester
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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