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RG 108

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Cat No.

CEI-0466

Description

A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming.

Alias

N-Phthalyl-L-tryptophan

Appearance

Yellow solid

Product Overview

A DNA methyltransferase (DNMT) inhibitor

CAS No.

48208-26-0

Molecular Weight

397.64

Purity

>98% by TLC

Storage

-20 centigrade

Synonyms

N-Phthalyl-L-tryptophan

Targets

DNMT1

Molecular Formula

C₁₉H₁₄N₂O₄

Solubility

DMSO (20 mg/ml)

Shipping Conditions

Gel pack