Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
Recombinant Human Histidine ammonia-lyase
Cat No.
EXWM-5289
Description
This enzyme is a member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.23 (tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase). The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is common to this family. This unique cofactor is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine. This enzyme catalyses the first step in the degradation of histidine and the product, urocanic acid, is further metabolized to glutamate.
Source
E.coli
Species
Human
Form
Liquid
Enzyme Commission Number
EC 4.3.1.3
CAS No.
9013-75-6
Molecular Weight
72.5 kDa
Purity
Greater than 80% as determined by SDS-PAGE.
Storage
Store at -80°C
Buffer
50 mM Tris-HCl, pH 8.0, 8 M urea
Reaction
L-histidine = urocanate + NH3
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Download
Download Datasheet