Description
Dopamine beta-hydroxylase (DBH) is a copper-containing mono-oxygenase that converts dopamine to norepinephrine in noradrenergic neurons, adrenergic neurons, and adrenal chromaffin cells. Therefore, DBH controls both norepinephrine synthesis and the dopamine/norepinephrine ratio in noradrenergic cells.
Enzyme Commission Number
EC 1.14.17.1
Activity
>7,000 pmol/min/μg
Molecular Weight
65-85 kDa
Purity
Greater than 95% as determined by SDS-PAGE.
Storage
Store at -20°C/-70°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reaction
dopamine + ascorbate + O2 = noradrenaline + dehydroascorbate + H2O
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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