The deoxynucleoside kinase NK12 is a mesophilic enzyme originating from Drosophila melanogaster. It phosphorylates deoxynucleosides to dNMPs using (d)ATP as phosphate donor. The enzyme differs from other 2'-deoxyribonucleoside kinases [EC 2.7.1.76 (2'-deoxyadenosine kinase) and EC 2.7.1.113 (deoxyguanosine kinase)] in its broad specificity for all four common deoxynucleosides. The quasi-irreversible transfer of phosphate from the high energy donor to the nucleoside enables high NMP yields.
Source
E.coli
Species
Drosophila melanogaster
Form
Liquid
Enzyme Commission Number
EC 2.7.1.145
Activity
Not detected
CAS No.
52227-81-3
Molecular Weight
30.5 kDa
Storage
Store at -20°C
Reaction
ATP + a 2'-deoxyribonucleoside = ADP + a 2'-deoxyribonucleoside 5'-phosphate
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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