Description
Highly specific for thyrotropin releasing hormone (pyroglutamyl-histidyl-prolylamide). Will not cleave the pyroglutamyl-histidyl bond of luteinizing hormone releasing hormone. Found in serum and brain. Inhibited by metal chelators. In peptidase family M1 (membrane alanyl aminopeptidase family)
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
thyroliberinase; pyroglutamyl aminopeptidase II; thyrotropin-releasing factor pyroglutamate aminopeptidase; pyroglutamate aminopeptidase II; pyroglutamyl peptidase II; thyroliberin-hydrolyzing pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading peptidase; TRH aminopeptidase
Reaction
Release of the N-terminal pyroglutamyl group from pGlu┼His-Xaa tripeptides and pGlu┼His-Xaa-Gly tetrapeptides
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.