Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
Purvalanol B
Cat No.
CEI-1104
Description
Cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Purvalanol B has also been shown to have antiproliferative properties, mediated by p42/p44 MAPK.
Abbr
Purvalanol B(CDK1, cyclin B, CDK2, CCNA2, cyclin E, CDK4, CCND1, CDK5, IL12A, )
Alias
CDC2, CDC28A, P34CDC2
Product Overview
Cyclin-dependent kinase inhibitor
CAS No.
212844-54-7
Molecular Weight
432.9
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
CDC2, CDC28A, P34CDC2
Targets
cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1, cdk5-p35
Molecular Formula
C20H25ClN6O3
Chemical Name
(R)-2-chloro-4-(2-(1-hydroxy-3-methylbutan-2-ylamino)-9-isopropyl-9H-purin-6-ylamino)benzoic acid
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Download
Download Datasheet