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Purine nucleoside phosphorylase, Recombinant

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Cat No.

NATE-0644

Description

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency.

Abbr

PUNP, Recombinant

Alias

PNPase; PUNPI; PUNPII

Source

E. coli

Applications

Purine nucleoside phosphorylase is used to study nucleotide salvage pathways and purine metabolism. It is used to study purine nucleoside phosphorylase deficiency and responsible PNP genetic mutations. This product is recombinant and expressed in E. coli.

Form

buffered aqueous solution (100 mM phosphate buffer with 1 mM MgCl2

Enzyme Commission Number

EC 2.4.2.1

Activity

> 120 U/mL

CAS No.

9030-21-1

Unit Definition

1 U will cause the phosphorolysis of 1 μmol of inosine to hypoxanthine and ribose 1-phosphate per minute at pH 7.4 at 25°C.

Storage

−20°C

Synonyms

purine-nucleoside phosphorylase; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; EC 2.4.2.1; 9030-21-1

"PNPase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
DIA-164	Native Bacillus sp. Purine Nucleoside Phosphorylase	EC 2.4.2.1	9030-21-1	Bacillus sp.	Inquiry
DIA-216	Native Microorganism Purine-nucleoside phosphorylase	EC 2.4.2.1	9030-21-1	Microorganism	Inquiry
NATE-0607	Nucleoside Phosphorylase from bacterial, Recombinant	EC 2.4.2.1	9030-21-1	E. coli	Inquiry
NATE-1000	Recombinant mutant (Met62Val) purine nucleoside phosphorylase from E. coli	EC 2.4.2.1	9030-21-1	E. coli	Inquiry

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