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Pioglitazone
Cat No.
CEI-0383
Description
Pioglitazone
Alias
Actos
CAS No.
111025-46-8
Molecular Weight
356.44
Purity
>99%
Storage
2 years at -20centigrade Powder
Synonyms
Actos
Targets
DPP4
Molecular Formula
C19H20N2O3S
Solubility
DMSO 15 mg/mL, Water
In vitro
Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator. Pioglitazone (Actos) selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) and to a lesser extent PPAR-alpha. Pioglitazone (Actos) modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the muscle, adipose tissue, and the liver. As a result, pioglitazone (Actos) reduces insulin resistance in the liver and peripheral tissues. Pioglitazone (Actos) increases the expense of insulin-dependent glucose. Pioglitazone (Actos) decreases withdrawal of glucose from the liver. Pioglitazone (Actos) reduces quantity of glucose, insulin and glycated hemoglobin in the bloodstream.
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