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Pimecrolimus
Cat No.
CEI-1025
Description
Pimecrolimus, a rapamycin (sirolimus) derivative, is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of inflammatory cytokines in T cells and mast cells and inhibits the release of preformed inflammatory mediators from mast cells.
Abbr
Pimecrolimus(Cytokine)
Appearance
white crystalline powder.
CAS No.
137071-32-0
Molecular Weight
810.4 Da
Purity
>99%
Stability
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Synonyms
Elidel, SDZ-ASM-981
Targets
Cytokine
Molecular Formula
C43H68ClNO11
Solubility
Soluble in DMSO and ethanol, up to about 25 mg/ml
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