Description
PIK-75, free base is a PI3K inhibitor displaying selectivity for the p110α isoform (IC50 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Alias
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Product Overview
PI3K inhibitor selectivity for the p110α isoform
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Molecular Formula
C16H14BrN5O4S
Chemical Name
(Z)-N'-((6-bromoH-imidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL