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phosphomethylpyrimidine synthase
Cat No.
EXWM-4931
Description
Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the S-adenosyl-L-methionine to produce L-methionine and a 5'-deoxyadenosin-5'-yl radical that is crucial for the conversion of the substrate. Part of the pathway for thiamine biosynthesis.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
thiC (gene name)
Reaction
5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine =4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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