Description
PF-04981517 is a potent and selective enzyme inhibitor of CYP3A4 with IC50 values of 0.03, 17 and 70 μM for CYP3A4, CYP3A5 and CYP3A7 respectively.
Abbr
PF-04981517(CYP3A4, CYP3A5, CYP3A7)
Alias
CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1
Synonyms
CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1
Targets
CYP3A4, CYP3A5, CYP3A7
IC50
0.03 μM, 17 μM, 70 μM
Molecular Formula
C26H32N8
Chemical Name
1-Methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
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