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peptidylprolyl isomerase

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Cat No.

EXWM-5450

Description

The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A. Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli. The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 5.2.1.8

CAS No.

95076-93-0

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

PPIase; cyclophilin [misleading, see comments]; peptide bond isomerase; peptidyl-prolyl cis-trans isomerase

Reaction

peptidylproline (ω=180) = peptidylproline (ω=0)

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

"Peptidylprolyl Isomerase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-0823	Cyclophilin A from Human, Recombinant	EC 5.2.1.8	95076-93-0	E. coli	Inquiry
NATE-0910	Peptidyl-Prolyl Cis/Trans Isomerase from Human, Recombinant			E. coli	Inquiry