Description
Peptidoglycan-N-acetylglucosamine deacetylase (EC 3.5.1.104, HP310, PgdA, SpPgdA, BC1960, peptidoglycan deacetylase, N-acetylglucosamine deacetylase, peptidoglycan GlcNAc deacetylase, peptidoglycan N-acetylglucosamine deacetylase, PG N-deacetylase) is an enzyme with systematic name peptidoglycan-N-acetylglucosamine amidohydrolase. This enzyme catalyses the following chemical reaction: peptidoglycan-N-acetyl-D-glucosamine + H2O → peptidoglycan-D-glucosamine + acetate. This enzyme contributes to virulence of Helicobacter pylori, Listeria monocytogenes and Streptococcus suis.
Abbr
SpPgdA, Recombinant (Streptococcus pneumoniae)
Species
Streptococcus pneumoniae
Form
35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol
Enzyme Commission Number
EC 3.5.1.-
Molecular Weight
24.2 kDa
Purity
>90% as judged by SDS-PAGE
Specificity
Peptidoglycan
Optimum temperature
37 °C
Storage
This enzyme is shipped at room temperature but should be stored at -20 °C.
Synonyms
Peptidoglycan-N-acetylglucosamine deacetylase; EC 3.5.1.-; HP310; PgdA; SpPgdA; BC1960; peptidoglycan deacetylase; N-acetylglucosamine deacetylase; peptidoglycan GlcNAc deacetylase; peptidoglycan N-acetylglucosamine deacetylase; PG N-deacetylase
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