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PD318088
Cat No.
CEI-0155
Description
PD318088
CAS No.
391210-00-7
Molecular Weight
561.09
Purity
>99%
Storage
2 years at -20 centigrade
Targets
MEK1/2
Molecular Formula
C16H13BrF3IN2O4
Solubility
No
In vitro
PD318088 is a small-molecule inhibitor of MEK1/2, which is an analog of PD184352, suggesting it might have substantial anti-proliferative activity against cancer cells, although no functional study of PD318088 is currently available. PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
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