Description
The egg envelope of the South African clawed frog (Xenopus laevis) is modified during transit of the egg through the pars rectus oviduct, changing the egg envelope from an unfertilizable form to a fertilizable form. This process involves the conversion of glycoprotein gp43 to gp41 (ZPC) by the pars recta protease oviductin. It is thought that the enzymically active protease molecule comprises the N-terminal protease domain coupled to two C-terminal CUB domains, which are related to the mammalian spermadhesin molecules implicated in mediating sperm-envelope interactions. The enzyme is also found in the Japanese toad (Bufo japonicus). Belongs in peptidase family S1.
Form
Liquid or lyophilized powder
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
oviductal protease
Reaction
Preferential cleavage at Gly-Ser-Arg373┼ of glycoprotein gp43 in Xenopus laevis coelemic egg envelope to yield gp41
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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