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NSC 66811
Cat No.
CEI-0556
Description
Cell-permeable. Potent MDM2 (murine double minute 2) inhibitor (Ki = 120 nM) that disrupts MDM2-p53 interaction and activates p53 in cancer cells. Induces p21, p53 and MDM2 accumulation in human colon cancer cells in vitro.
Appearance
White to off-white solid
Product Overview
Potent MDM2 inhibitor
CAS No.
6964-62-1
Molecular Weight
302.41
Purity
>98%
Storage
-20 centigrade
Targets
MDM2
Molecular Formula
C 23 H 20 N 2 O
Chemical Name
2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol
Solubility
DMSO (10 mg/ml) or EtOH (10 mg/ml)
Shipping Conditions
Gel pack
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