Description
Exposure to sunlight and aging can cause the skin to develop brown spots, often due to overactive melanocytes that secrete excessive melanin. The melanocyte-stimulating hormone, alpha-MSH (α-MSH), has a physiological effect that induces skin pigmentation. When α-MSH binds to its specific receptor MC1-R on melanocytes, it activates tyrosinase, thereby initiating the melanin synthesis pathway.
Nonapeptide-1 is a bio-structural mimic of α-MSH and has a high affinity for the specific receptor MC1-R. It competitively inhibits the binding of α-MSH to MC1-R, preventing the activation of tyrosinase and ultimately reducing excessive melanin production. This helps restore the skin to its normal color.
Applications
Nonapeptide-1 can be used in products designed to brighten the skin, balance skin tone, and in treatments for photoaging and age spots.
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