Description
Alcohol dehydrogenase [NADP+] also known as aldehyde reductase or aldo-keto reductase family 1 member A1 is an enzyme that in humans is encoded by the AKR1A1 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Alternative splicing of this gene results in two transcript variants encoding the same protein.
Abbr
ALR, Native (Thermoanaerobium sp.)
Alias
ALR 1; AKR1A1; ALDR1; ALR
Source
Thermoanaerobium sp.
Enzyme Commission Number
EC 1.1.1.2
Activity
1-5 units/mg solid
Composition
Protein, ~5% Bradford
Unit Definition
One unit will oxidize 1.0 μmole of 2-propanol to acetone per min at pH 9.0 at 50°C.
Buffer
Lyophilized powder containing raffinose, dithiothreitol, and potassium phosphate buffer salt.
Synonyms
EC 1.1.1.2; Aromatic Alcohol Dehydrogenase; Alcohol:NADP+ oxidoreductase; AKR1A1; ALDR1; ALR; ARM; DD3; HEL-S-6; aldehyde reductase; aldo-keto reductase family 1 member A1; alcohol dehydrogenase (NADP+); aldehyde reductase (NADPH2); NADP-alcohol dehydrogenase; NADP+-aldehyde reductase; NADP+-dependent aldehyde reductase; NADPH-aldehyde reductase; NADPH-dependent aldehyde reductase; nonspecific succinic semialdehyde reductase; ALR 1; low-Km aldehyde reductase; high-Km aldehyde reductase; alcohol dehydrogenase (NADP)