Description
Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline. Calcium is required for peptidylarginine deiminase activity in vitro.
Abbr
PAD, Native (Rabbit)
Source
Rabbit skeletal muscle
Applications
Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis.
Product Overview
Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline.
Form
buffered aqueous glycerol solution; Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol
Enzyme Commission Number
EC 3.5.3.15
Activity
> 200 units/mg protein (Bradford)
Unit Definition
One unit will produce 1 μmole of N-α-benzoylcitrulline ethyl ester from BAEE per hr at 55°C at pH 7.2.
Synonyms
protein-arginine deiminase; peptidylarginine deiminase; PAD; EC 3.5.3.15; 75536-80-0
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