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Native Porcine Creatine Kinase MM

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Cat No.

NATE-0959

Description

Creatine kinase, muscle also known as CKM is a creatine kinase that in humans is encoded by the CKM gene. In the figure to the right, the crystal structure of the muscle-type M-CK monomer is shown. In vivo, two such monomers arrange symmetrically to form the active MM-CK enzyme. In heart, in addition to the MM-CK homodimer, also the heterodimer MB-CK consisting of one muscle (M-CK) and one brain-type (B-CK) subunit is expressed. The latter may be an important serum marker for myocardial infarction, if released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.

Abbr

CK-MM, Native (Porcine)

Alias

CK-MM

Source

Porcine Skeletal Muscle

Species

Porcine

Applications

Diagnostic Controls, Calibrators & Standards; Clinical Chemistry; Testing/Assay Validation; Life Science; Manufacturing

Form

Liquid; 50% Glycerol, 50 mM TrisCl, 2.5 mM b-mercaptoethanol, 0.05% NaN3

Molecular Weight

43 kDa

Purity

> 90% (SDS-PAGE)

Concentration

> 1.0 mg/mL

Optimum pH

Typically 8.0

Stability

2 years

Storage

Store at -20°C

Synonyms

CKM; creatine kinase, muscle; CKMM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; M-CK; MM-CK

"CK" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1887	Native Mouse Creatine Kinase MM			Mouse Skeletal Muscle	Inquiry
NATE-1885	Native Human Creatine Kinase BB	EC 2.7.3.2	9001-15-4	Human Brain	Inquiry
NATE-1884	Native Porcine Creatine Kinase	EC 2.7.3.2	9001-15-4	Porcine Heart	Inquiry
NATE-1883	Native Human Creatine Kinase MM	EC 2.7.3.2	9001-15-4	Human Skeletal Muscle	Inquiry

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