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Native Porcine Colipase
Cat No.
NATE-0144
Description
Colipase is a protein co-enzyme required for optimal enzyme activity of pancreatic lipase. It is secreted by the pancreas in an inactive form, procolipase, which is activated in the intestinal lumen by trypsin. Its function is to prevent the inhibitory effect of bile salts on the lipase-catalyzed intraduodenal hydrolysis of dietary long-chain triglycerides. In humans, the colipase protein is encoded by the CLPS gene.
Abbr
CLPS, Native (Porcine)
Alias
CLPS; colipase
Source
Porcine pancreas
Species
Porcine
Applications
Pancreatic colipase is a required co-factor for pancreatic lipase, being necessary for its activity during hydrolysis of dietary triglycerides in the presence of bile salts
Appearance
Colourless liquid
Form
Liquid
Activity
10 KU-20 KU/mL
Contaminants
Glucose Oxidase < 0.002 U/mg liquid
Concentration
0.15-0.52 mg/mL
Unit Definition
One unit of activity is defined as the amount of enzyme that will catalyze the release of 1.0 micromole of fatty acid from tributyrin per minute at 20°C under the standard assay method conditions.
Pathway
Digestion of dietary lipid, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem
Function
enzyme activator activity
Synonyms
CLPS; colipase; pancreatic colipase
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