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Native Human Glutathione Peroxidase

Cat No.
NATE-0323
Description
Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown.
Abbr
GSH-Px, Native (Human)
Alias
GSH-Px
Source
Human erythr ocytes
Species
Human
Product Overview
At the reported pH optimum of 8.8, we have found the activity to be approx. 10 times that at pH 7.0. However, to remain consistent with literature and avoid complications arising from non-enzymatic oxidation of GSH, our unit is defined at pH 7.0.
Form
Lyophilized powder containing 25% sucrose, 3% dithiothreitol, and sodium phosphate buffer salts
Enzyme Commission Number
EC 1.11.1.9
Activity
> 30 units/mg protein
CAS No.
9013-66-5
pH Stability
8.8
Unit Definition
One unit will catalyze the oxidation by H2O2 of 1.0 μmole of reduced glutathione to oxidized glutathione per min at pH 7.0 at 25°C.
Optimum pH
8.8
Storage
−20°C
Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem
Function
SH3 domain binding; endopeptidase inhibitor activity; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity
Synonyms
EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase

"GSH-Px" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-0322 Native Bovine Glutathione Peroxidase EC 1.11.1.9 9013-66-5 Bovine erythr ocytes Inquiry
EXWM-0511 glutathione peroxidase EC 1.11.1.9 9013-66-5 Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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