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Native Human Creatine Kinase MB Fraction

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Cat No.

NATE-0141

Description

In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes:CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes:B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form. The functional entity of the latter two mitochondrial CK isoforms is an octamer consisting of four dimers each.

Abbr

CKMB, Native (Human)

Alias

CK-MB; CKMB; Creatine Kinase MB

Source

Human heart

Species

Human

Applications

The MB isoenzyme of creatine kinase (MBCK) can be used as a diagnostic marker for acute myocardial infarction.

Form

liquid

Purity

> 70% (SDS-PAGE)

Concentration

> 0.5 mg/mL

Stability

−20°C

Buffer

Solution in 5 mM sodium succinate, 10 mM sodium chloride, 1 mM EDTA, 5 mM β-mercaptoethanol, 50% glycerol, pH 7.0.

Synonyms

CK-MB; CKMB; Creatine Kinase MB Fraction; Creatine Kinase MB

"CK" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1887	Native Mouse Creatine Kinase MM			Mouse Skeletal Muscle	Inquiry
NATE-1885	Native Human Creatine Kinase BB	EC 2.7.3.2	9001-15-4	Human Brain	Inquiry
NATE-1884	Native Porcine Creatine Kinase	EC 2.7.3.2	9001-15-4	Porcine Heart	Inquiry
NATE-1883	Native Human Creatine Kinase MM	EC 2.7.3.2	9001-15-4	Human Skeletal Muscle	Inquiry

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