Description
Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin, an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene.
Abbr
A2AP, Native (Human)
Molecular Weight
63-70 kDa
Pathway
Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem; Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem
Function
endopeptidase inhibitor activity; eukaryotic cell surface binding; protease binding; protein binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity
Synonyms
Alpha-2 Antiplasmin; α2-antiplasmin; plasmin inhibitor; SERPINF2; A2AP; AAP; ALPHA-2-PI; API; PLI