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Native Flavobacterium heparinum Heparinase I and III Blend

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Cat No.

NATE-0337

Description

Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides.

Abbr

Heparinase I and III, Native (Flavobacterium heparinum)

Alias

Heparinase

Source

Flavobacterium heparinum

Applications

Heparinase I and III may be used for the study of heparin production during fermentation and specific activity of heparinise.

Product Overview

Heparinase is an inducible, non-extracellular heparin-degrading enzyme. Three types of heparinises are produced by Flavobacterium heparinum and contains specific sequences of heparin.

Unit Definition

One unit will form 0.1 micromole of unsaturated uronic acid per hour at 7.5 at 25 degrees C using Heparin, Sodium as substrate for heparinase I. One unit will form 0.1 micromole of unsaturated uronic acid per hour at 7.5 at 25 degrees C using bovine kidney Heparan, Sulfate as substrate for heparinase III.

Storage

−20°C

Warnings

Enzyme Commission Numbers: 4.2.2.7 Hep I and 4.2.2.8 Hep III

Synonyms

Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I; Heparinase III

"Heparinase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1948	Heparinase III from Flavobacterium heparinum, Recombinant	EC 4.2.2.8	37290-86-1	E.coli	Inquiry
NATE-1947	Heparinase II from Flavobacterium heparinum, Recombinant		149371-12-0	E.coli	Inquiry
NATE-1946	Heparinase I from Flavobacterium heparinum, Recombinant	EC 4.2.2.7	9025-39-2	E.coli	Inquiry
NATE-0338	Native Flavobacterium heparinum Heparinase I	EC 4.2.2.7	9025-39-2	Flavobacterium heparinum	Inquiry

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