Description
Glutaminase catalyzes the conversion of glutamine to glutamate. Glutaminase is an amidohydrolase enzyme that generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Glutaminase has an important role in glial cells. Glutaminase catalyzes the following reaction:Glutamine + H2O → Glutamate + NH3.
Abbr
Glutaminase, Native (E. coli)
Form
Type I, Lyophilized powder containing stabilizer and potassium succinate; Type II, Lyophilized powder containing potassium succinate and EDTA.
Enzyme Commission Number
EC 3.5.1.2
Activity
Type I, 500-1,500 units/mg protein; Type II, 50-200 units/mg protein.
Unit Definition
One unit will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37°C.
Synonyms
EC 3.5.1.2; glutaminase I; L-glutaminase; glutamine aminohydrolase; Glutaminase; 9001-47-2