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Native Electrophorus electricus (electric eel) Acetylcholinesterase

Cat No.
NATE-0018
Description
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a hydrolase that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Abbr
AChE, Native (Electrophorus electricus (electric eel))
Alias
AChE; AcCholE; Acetyl
Source
Electrophorus electricus (electric eel)
Applications
The enzyme has been used as a reference to to evaluate the effect of aspartame metabolites on hippocampal acetylcholinesterase activity. The enzyme has also been used in immobilization studies for the rapid detection of acetylthiocholine chloride.
Product Overview
Type VI-S, lyophilized powder, 200-1000 units/mg protein; Type V-S, lyophilized powder, > 1000 units/mg protein
Form
lyophilized powder
Enzyme Commission Number
EC 3.1.1.7
Activity
> 1 ,000 units/mg protein; 200-1 ,000 units/mg protein
CAS No.
9000-81-1
Molecular Weight
280 kDa
Isoelectric point
~5.3
Unit Definition
One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37°C.
Storage
−20°C
Buffer
Tris buffer: soluble 1 mg/mL (0.02 M Tris buffer, pH 7.5)
Synonyms
true cholinesterase; choline esterase I; cholinesterase; acetylthiocholinesterase; acetylcholine hydrolase; acetyl; β-methylcholinesterase; AcCholE; EC 3.1.1.7; 9000-81-1; Acetylcholinesterase; AChE; acetylhydrolase

"Acetylcholinesterase" Total Products Page

Catalog Product Name EC No. CAS No. Source Price
NATE-0019 Native Human erythrocytes Acetylcholinesterase EC 3.1.1.7 9000-81-1 Human erythrocytes Inquiry
NATE-0020 Acetylcholinesterase Human, Recombinant EC 3.1.1.7 9000-81-1 HEK 293 cells Inquiry
EXWM-3497 acetylcholinesterase EC 3.1.1.7 9000-81-1 Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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