Description
In enzymology, a nucleotide diphosphatase (EC 3.6.1.9) is an enzyme that catalyzes the chemical reaction:a dinucleotide + H2O↔ 2 mononucleotides. Thus, the two substrates of this enzyme are dinucleotide and H2O, whereas its product is mononucleotide. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. This enzyme participates in 5 metabolic pathways:purine metabolism, starch and sucrose metabolism, riboflavin metabolism, nicotinate and nicotinamide metabolism, and pantothenate and coa biosynthesis.
Abbr
Nucleotide Pyrophosphatase, Native (Crotalus adamanteus venom)
Source
Crotalus adamanteus venom
Package
vial of ~25 units
Form
Lyophilized powder containing approx. 35% Tris buffer salts.
Enzyme Commission Number
EC 3.6.1.9
Activity
4-8 units/mg protein, vial of ~25 units
Unit Definition
One unit will hydrolyze 1.0 μmole of β-NAD to NMN and AMP per min at pH 7.4 at 37°C in the presence of Mg ions.
Synonyms
nucleotide diphosphatase; EC 3.6.1.9; nucleotide pyrophosphatase; nucleotide-sugar pyrophosphatase; 9032-64-8
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