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Native Bovine Cathepsin B

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Cat No.

NATE-0167

Description

Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of Rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced.

Abbr

CTSB, Native (Bovine)

Alias

CTSB; cathepsin B; APPS; CPSB

Source

Bovine spleen

Species

Bovine

Form

Lyophilized powder containing sodium phosphate, sodium chloride and ~6% EDTA as stabilizer.

Activity

> 10 units/mg protein

CAS No.

9047-22-7

Composition

Protein, > 30% biuret

Unit Definition

One unit will hydrolyze 1 μmole of Z-lysine p-nitrophenyl ester per min at pH 5.0 at 25°C.

Pathway

Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Assembly of collagen fibrils and other multimeric structures, organism-specific biosystem

Function

collagen binding; cysteine-type endopeptidase activity; proteoglycan binding

Synonyms

CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II

"Cathepsin B" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1706	Cathepsin B from Human, recombinant	EC 3.4.22.1	9047-22-7	E. coli	Inquiry
NATE-0168	Native Human Cathepsin B	EC 3.4.22.1	9047-22-7	Human liver	Inquiry
NATE-0169	Native Human Cathepsin B	EC 3.4.22.1	9047-22-7	Human placenta	Inquiry
EXWM-4192	cathepsin B	EC 3.4.22.1	9047-22-7		Inquiry

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