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Native Bovine Cathepsin B
Cat No.
NATE-0167
Description
Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of Rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced.
Abbr
CTSB, Native (Bovine)
Alias
CTSB; cathepsin B; APPS; CPSB
Source
Bovine spleen
Species
Bovine
Form
Lyophilized powder containing sodium phosphate, sodium chloride and ~6% EDTA as stabilizer.
Activity
> 10 units/mg protein
CAS No.
9047-22-7
Composition
Protein, > 30% biuret
Unit Definition
One unit will hydrolyze 1 μmole of Z-lysine p-nitrophenyl ester per min at pH 5.0 at 25°C.
Pathway
Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Assembly of collagen fibrils and other multimeric structures, organism-specific biosystem
Function
collagen binding; cysteine-type endopeptidase activity; proteoglycan binding
Synonyms
CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II
Download
Download Datasheet"Cathepsin B" Total Products Page
| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1706 | Cathepsin B from Human, recombinant | EC 3.4.22.1 | 9047-22-7 | E. coli | Inquiry |
| NATE-0168 | Native Human Cathepsin B | EC 3.4.22.1 | 9047-22-7 | Human liver | Inquiry |
| NATE-0169 | Native Human Cathepsin B | EC 3.4.22.1 | 9047-22-7 | Human placenta | Inquiry |
| EXWM-4192 | cathepsin B | EC 3.4.22.1 | 9047-22-7 | Inquiry |