Description
Nucleoside 5'-diphosphate kinase is a cytosolic enzyme. Nucleoside 5'-diphosphate kinase from Saccharomyces cerevisiae is found highly expressed in the cytoplasm. It affects DNA synthesis, in part, by binding to Cdc8p.
Abbr
NDPK, Native (Baker's Yeast (S. cerevisiae))
Source
Baker's yeast (S. cerevisiae)
Applications
Nucleoside 5′-diphosphate kinase has been used in a study to examine a possible intracellular activity of the drug disodium cromoglycate in mast cells. It has also been used in a study to investigate protein synthesis in rabbit reticul ocytes.
Product Overview
Nucleoside 5′-diphosphate kinase is a cytosolic enzyme.
Form
lyophilized powder; essentially sulfate-free powder. Contains sodium Citrate with a trace of magnesium and EDTA salts.
Enzyme Commission Number
EC 2.7.4.6
Unit Definition
One unit will convert 1.0 μmole each of TDP and ATP to TTP and ADP per min at pH 7.6 at 25°C in a coupled system with PK/LDH.
Buffer
Reconstitute with deionized water. Solution is believed to be stable for over 1 year while frozen.
Synonyms
nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridine diphosphate kinase; nucleoside-diphosphate kinase; EC 2.7.4.6; 9026-51-1; NDPK
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