Products

Online Inquiry

Name

Email *

Phone *

Company/Institution

Country or Region

Quantity

Services & Products Interested *

Project Description

Our Products Cannot Be Used As Medicines Directly For Personal Use.

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Native Bacillus sphaericus 12α-Hydroxysteroid Dehydrogenase

inquiry

Cat No.

NATE-0001

Description

In enzymology, a 12alpha-hydroxysteroid dehydrogenase (EC 1.1.1.176) is an enzyme that catalyzes the chemical reaction:3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + NADP+↔ 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+. Thus, the two substrates of this enzyme are 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate and NADP+, whereas its 3 products are 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. This enzyme is involved in a metabolic pathway that degrades bile acids into cholesterol.

Abbr

12α-Hydroxysteroid Dehydrogenase, Native (Bacillus sphaericus)

Source

Bacillus sphaericus

Form

lyophilized powder

Enzyme Commission Number

EC 1.1.1.176

Activity

150-350 units/mg protein (Lowry)

CAS No.

61642-40-8

Unit Definition

One unit will oxidize 1.0 μmole of deoxycholic acid to 12-ketodeoxycholic acid per min at pH 8.0 at 37°C.

Storage

−20°C

Synonyms

EC 1.1.1.176; 61642-40-8; 12α Hydroxysteroid Dehydrogenase; 12alpha-hydroxy steroid dehydrogenase; NAD+-dependent 12alpha-hydroxysteroid dehydrogenase; NADP+-12alpha-hydroxysteroid dehydrogenase; 12-α-Hydroxysteroid Dehydrogenase; 12alpha-hydroxysteroid:NADP+ 12-oxidoreductase

"12α-Hydroxysteroid Dehydrogenase" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
EXWM-0079	12α-hydroxysteroid dehydrogenase	EC 1.1.1.176	61642-40-8		Inquiry