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Native α-1,2-Fucosidase solution

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Cat No.

NATE-0259

Description

Tissue alpha-L-fucosidase is an enzyme that in humans is encoded by the FUCA1 gene. Alpha-Fucosidase is an enzyme that breaks down fucose. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form; coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form; and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.

Abbr

FUCA, Native

Alias

FUCA1; FUCA

Package

vial of 0.004 unit

Form

buffered aqueous solution, Solution in 20 mM Tris-HCl, pH 7.5, 25 mM NaCl

Enzyme Commission Number

EC 3.2.1.51

Activity

> 0.4 units/mg protein

CAS No.

9037-65-4

Unit Definition

One unit will release 1.0 μmole of fucose from 2′-fucosyllactose per min at pH 5.0 at 37°C

Storage

2-8°C

Pathway

Lysosome, organism-specific biosystem; Other glycan degradation, organism-specific biosystem

Function

alpha-L-fucosidase activity; carbohydrate binding

Synonyms

α-1,2-Fucosidase; alpha-L-fucosidase; Alpha-Fucosidase; FUCA1; FUCA; 9037-65-4

"FUCA" Total Products Page

Enzymes

Catalog	Product Name	EC No.	CAS No.	Source	Price
NATE-1258	α(1-2) Fucosidase from Xanthomonas manihotis, Recombinant			E. coli	Inquiry
NATE-0266	Native Bovine α-L-Fucosidase	EC 3.2.1.51	9037-65-4	Bovine kidney	Inquiry
NATE-0749	Native environmental DNA α-Fucosidase	EC 3.2.1.51	9037-65-4	Proprietary environmental DNA	Inquiry
NATE-0261	Native Bovine α (1-2,3,4,6) Fucosidase			Bovine kidney	Inquiry

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