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Mubritinib(TAK 165)

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Cat No.

CEI-0033

Description

Mubritinib(TAK 165)

Alias

TAK 165, TAK165

CAS No.

366017-09-6

Molecular Weight

468.47

Purity

>99%

Storage

2 years at -20 centigrade

Synonyms

TAK 165, TAK165

Targets

ErbB2

Molecular Formula

C25H23F3N4O2

Solubility

In vitro

TAK-165 can inhibit HT1376, UMUC3, T24 (bladder), ACHN (kidney), DU145, LNCaP, LN-REC4 (prostate) cell lines, which are observed HER2 expression, with IC50 from 0.09 to greater than 25 micromol/L. The prostate cancer cell lines are all sensitive to mubritinib (TAK 165).Mubritinib (TAK 165) can inhibit prostate cancer cell lines with IC50 from 0.053to 4.62 micromol/L.