Description
Motesanib (AMG 706) is a multi-targeted anticancer agent with an inhibitory action on human vascular endothelial growth factor receptors 1, 2 and 3 (VEGFR1-3), platelet-derived growth factor receptor (PDGFR) and cellular stem-cell factor receptor (c-KIT).
Abbr
Motesanib(KIT, PDGFRB, KDR)
Alias
C-Kit, CD117, PBT, SCFR
Product Overview
Inhibitor of human vascular endothelial growth factor receptors 1, 2 and 3 (VEGFR1-3), platelet-derived growth factor receptor (PDGFR) and cellular stem-cell factor receptor (c-KIT)
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Synonyms
C-Kit, CD117, PBT, SCFR
Targets
c-Kit, PDGFR, VEGFR
Molecular Formula
C22H23N5O
Chemical Name
N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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