Description
Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient macrophages
Appearance
White to off-white solid
Product Overview
A migration inhibitory factor (MIF) antagonist
Molecular Formula
C₁₂H₁₃NO₄
Chemical Name
(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester
Solubility
DMSO (40 mg/ml) or EtOH (40 mg/ml)
Shipping Conditions
Gel pack
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