Description
A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration inhibitory factor) inhibitor. It occupies an interface of MIF trimers, leading to the loss of its tautomerase, receptor binding, and pro-inflammatory activities. An excellent tool to design MIF-directed therapeutics for inflammatory diseases.
Alias
Chicago Sky blue 6B
Appearance
Off-white solid
Product Overview
An allosteric MIF (macrophage migration inhibitory factor) inhibitor
Synonyms
Chicago Sky blue 6B
Molecular Formula
C 34 H 24 N 6 Na 4 O 16 S 4
Chemical Name
6,6-[(3,3-Dimethoxy[1,1-biphenyl]-4,4-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonic acid] tetrasodium salt