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MG-115

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Cat No.

CEI-0623

Description

A potent, reversible proteasome inhibitor with Ki of 21 nM for 20S proteasome and 35 nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome. Also shown to induce apoptosis in Rat-1 and PC12 cells via a p3-independent pathway.

Alias

Z-LLNVa-CHO; Z-Leu-Leu-NVa-CHO

Appearance

White solid

Product Overview

A proteasome inhibitor

CAS No.

133407-86-0

Molecular Weight

390.51

Purity

>95% by HPLC

Storage

-20 centigrade

Synonyms

Z-LLNVa-CHO; Z-Leu-Leu-NVa-CHO

Targets

protease

Molecular Formula

C₂₅H₃₉N₃O₅

Solubility

DMSO (20 mg/ml) or Ethanol (25 mg/ml)

Shipping Conditions

Gel pack

"Protease" Total Products Page

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