Description
Lysostaphin is a Staphylococcus simulans metalloendopeptidase. It can function as an antimicrobial against Staphylococcus aureus. Lysostaphin is a 27 KDa glycylglycine endopeptidase, an antibacterial enzyme which is capable of cleaving the crosslinking pentaglycin bridges in the cell wall of Staphylococci.
Abbr
Lysostaphin, Recombinant (Staphylococcus simulans)
Species
Staphylococcus simulans
Applications
Lysostaphin from Staphyl oc occus simulans has been used in a study to assess molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphyl oc occus aureus. It has also been used in a study to investigate the sequence analysis of a Staphyl oc occus aureus gene encoding a peptidoglycan hydrolase activity.
Form
Type I, lyophilized powder, Contains potassium phosphate buffer salts and sodium chloride; Type II, lyophilized powder.
Enzyme Commission Number
EC 3.4.24.75
Activity
Type I, > 2,000 units/mg protein; Type II, > 500 units/mg protein.
Synonyms
Lysostaphin; EC 3.4.24.75; glycyl-glycine endopeptidase; 9011-93-2
Download Datasheet